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LAB EQUIPMENT REPAIRS, INCLUDING ULTRALOW FREEZERS, FRIDGES, CENTRIFUGES AND MORE - Click here for details
LAB EQUIPMENT REPAIRS, INCLUDING ULTRALOW FREEZERS, FRIDGES, CENTRIFUGES AND MORE - Click here for details

Hirayama HV-50II vertical autoclave – demo unit

Fully Tested & Warrantied*
Brand : Amerex
Product Code : SKU 0580DD A-CLAVE
Date In: 04/16/2025

Shipping

All products ship from our 30,000 sq. ft. Haverhill, MA warehouse

Hirayama HV-50II Vertical Autoclave

Laboratories rely on dependable steam sterilization to maintain research integrity, laboratory safety, and efficient daily workflows. Whether sterilizing culture media, laboratory glassware, reusable instruments, or biohazardous waste, an autoclave plays a critical role in keeping laboratory operations moving. The refurbished Hirayama HV-50II Vertical Autoclave from American Instrument Exchange provides a reliable 50-liter sterilization solution for biotechnology companies, pharmaceutical manufacturers, academic research laboratories, clinical laboratories, and industrial testing facilities seeking professional sterilization performance at a lower cost than purchasing new equipment.

Designed with a compact vertical footprint and programmable controls, the Hirayama HV-50II combines laboratory-grade performance with efficient use of floor space. As a professionally inspected and tested refurbished autoclave, it provides laboratories with an economical way to expand sterilization capacity, replace aging equipment, or reduce downtime when an existing autoclave unexpectedly fails.

Hirayama HV-50II Key Features

  • 50-liter vertical steam sterilizer

  • Programmable sterilization and warming cycles

  • Maximum sterilization temperature up to 135°C

  • Stainless steel pressure chamber

  • Automatic pressure and temperature control

  • Multiple safety interlocks with low-water protection

  • Compact footprint for efficient laboratory installation

  • Refurbished, inspected and tested by American Instrument Exchange

  • Includes a 90-day warranty

Overview

The Hirayama HV-50II is a versatile vertical laboratory autoclave designed for routine steam sterilization across a wide range of laboratory environments. Its compact design makes it particularly useful for laboratories where floor space is limited, while its 50-liter chamber provides sufficient capacity for instruments, glassware, media, liquids, and laboratory waste.

Unlike larger floor-mounted sterilizers that may require extensive facility modifications, the HV-50II offers a practical balance between chamber capacity and installation flexibility. Its programmable operating modes allow users to select sterilization parameters appropriate for different load types, helping protect sensitive materials while supporting effective and repeatable sterilization cycles.

For laboratories replacing an aging autoclave or expanding sterilization capacity, purchasing a refurbished Hirayama HV-50II from American Instrument Exchange can significantly reduce capital costs while maintaining dependable laboratory operation. Because many refurbished systems are in stock and ready to ship, laboratories may be able to restore sterilization capacity more quickly than they could by waiting through extended factory lead times for new equipment.

Hirayama HV-50II Vertical Autoclave Common Applications

  • Sterilization of laboratory glassware

  • Preparation and sterilization of microbiological media

  • Sterilization of reusable laboratory instruments

  • Cell culture support applications

  • Biohazardous waste decontamination

  • Pharmaceutical quality control

  • Biotechnology research

  • Academic laboratory research

  • Clinical laboratory sterilization

  • Environmental and industrial testing

HV-50II Vertical Autoclave Ideal Laboratory Environments

The Hirayama HV-50II is well suited for laboratories that require dependable sterilization without the footprint or infrastructure demands of a larger institutional sterilizer. Biotechnology companies may use vertical autoclaves for preparing culture media and sterilizing reusable laboratory equipment, while microbiology laboratories rely on them for processing contaminated materials and maintaining sterile workflows. Academic research laboratories can benefit from the combination of programmable controls, useful chamber capacity, and a relatively compact design.

The HV-50II may also be appropriate for pharmaceutical quality control laboratories, environmental testing facilities, food and beverage laboratories, veterinary diagnostic laboratories, contract research organizations, and industrial quality assurance operations where reliable steam sterilization supports routine laboratory work.

Sterilization Capabilities

Steam sterilization is a widely used method for reducing or eliminating bacteria, viruses, fungi, spores, and other microorganisms from compatible laboratory materials. The Hirayama HV-50II is designed to process a broad range of laboratory loads, including reusable glassware, stainless steel instruments, microbiological media, culture vessels, laboratory utensils, and biohazardous waste.

Programmable sterilization cycles allow laboratories to select operating conditions appropriate for different materials and load types. This helps support effective sterilization while minimizing unnecessary heat exposure. For laboratories performing daily sterilization tasks, repeatable and controlled cycles can contribute to greater consistency across research, quality control, testing, and production workflows.

Customers should confirm that the selected cycle and load configuration are appropriate for the materials being sterilized. Liquids, instruments, waste, wrapped goods, and other load types may require different cycle settings and handling procedures.

Hirayama HV-50II Chamber Capacity and Laboratory Workflow

With its approximately 50-liter chamber, the Hirayama HV-50II provides sufficient capacity for many routine laboratory sterilization tasks while maintaining a relatively compact overall footprint. The vertical loading configuration makes efficient use of floor space and allows operators to process larger batches than may be practical in many small benchtop autoclaves.

For laboratories balancing multiple research projects, testing programs, or production activities, dependable sterilization capacity directly supports productivity. A reliable autoclave can reduce workflow interruptions, help laboratories maintain experimental schedules, and minimize delays associated with equipment failure.

For organizations replacing an aging or nonfunctional sterilizer, choosing an in-stock refurbished autoclave from American Instrument Exchange may significantly reduce downtime compared with waiting for new equipment to be manufactured and delivered.

Choosing the Right Laboratory Autoclave

Selecting an autoclave involves more than choosing the largest available chamber. Laboratories should evaluate expected load types, chamber capacity, sterilization temperature, cycle programming, utility requirements, workflow volume, and future sterilization needs before making a purchase.

The Hirayama HV-50II is a strong option for laboratories seeking a versatile vertical steam sterilizer capable of handling routine sterilization without the size or installation demands of a larger hospital-grade system. Its combination of chamber capacity, programmable operation, and compact design makes it especially useful for research laboratories, biotechnology companies, microbiology facilities, and quality control departments seeking to improve sterilization capacity while controlling equipment costs.

American Instrument Exchange can help laboratories review their sterilization requirements and determine whether the Hirayama HV-50II is appropriate for their available space, utilities, workload, and budget.

Hirayama Laboratory Autoclaves

Hirayama is known for manufacturing laboratory autoclaves used in research, biotechnology, pharmaceutical, healthcare, and industrial environments. Hirayama sterilizers are designed for scientific and laboratory workflows, with an emphasis on practical operation, reliable pressure vessel construction, programmable functionality, and consistent sterilization performance.

The HV-50II reflects Hirayama’s focus on efficient laboratory sterilization by combining useful chamber capacity with straightforward controls and a compact vertical configuration. Professionally refurbished Hirayama autoclaves can provide laboratories with access to proven sterilization technology at a substantial savings compared with purchasing new equipment.

Hirayama HV-50II Key Specifications

Specification
Manufacturer Hirayama
Model HV-50II
Sterilizer Type Vertical steam autoclave
Chamber Capacity 50 L
Chamber Dimensions Approximately 325 mm Ø × 600 mm H (12.8 in Ø × 23.6 in H)
Exterior Dimensions Approximately 500 × 660 × 1,040 mm (19.7 × 26.0 × 40.9 in)
Chamber Material Stainless steel
Maximum Sterilization Temperature Up to 135°C
Sterilization Programs Programmable
Safety Features Pressure interlock, low-water protection, and automatic controls
Control System Digital programmable controller
Electrical Requirements Verify the configuration of the available unit before purchase
Condition Refurbished
Warranty 90 days

Specifications should be confirmed against the individual unit, equipment data plate, and available manufacturer documentation before purchase.

Installation and Utility Requirements

The Hirayama HV-50II is designed for installation in a variety of laboratory environments. Before purchasing, laboratories should verify the available electrical service, room dimensions, operating clearances, ventilation, and any water or drainage requirements associated with the unit.

Electrical and utility configurations may vary between individual systems. American Instrument Exchange can help customers confirm the specifications and installation requirements of the available autoclave before shipment.

Proper installation, operator training, routine cleaning, and preventive maintenance can help support reliable sterilization performance and extend the service life of the equipment.

Why Buy a Refurbished Autoclave from American Instrument Exchange?

Purchasing a refurbished autoclave from American Instrument Exchange allows laboratories to acquire dependable sterilization equipment while reducing capital expenditures compared with purchasing new. Each refurbished autoclave is inspected and tested by our technicians before shipment to verify proper operation.

American Instrument Exchange maintains an extensive inventory of used and refurbished laboratory equipment, including biosafety cabinets, CO₂ incubators, laboratory refrigerators, ultralow freezers, centrifuges, glassware washers, laboratory ovens, and other essential equipment. With many systems in stock and ready to ship, laboratories can often restore operations more quickly than they could by waiting through extended manufacturer lead times.

Customers can contact American Instrument Exchange to discuss equipment availability, utility requirements, shipping, and whether the Hirayama HV-50II is suitable for their laboratory workflow.

Frequently Asked Questions

Can the Hirayama HV-50II sterilize liquids and microbiological media?

The HV-50II is designed to process laboratory loads that may include liquids and microbiological media when the appropriate cycle, containers, loading method, and operating procedures are used. Customers should verify that the available unit includes the cycle capabilities required for their applications.

Is the Hirayama HV-50II suitable for biotechnology laboratories?

Yes. Its chamber capacity, programmable operation, and vertical configuration make it suitable for many biotechnology, microbiology, pharmaceutical quality control, and academic research laboratories.

What types of materials can be processed in this autoclave?

Depending on the selected cycle and laboratory procedures, the HV-50II may be used for compatible glassware, instruments, culture media, liquids, laboratory utensils, and biohazardous waste. Materials should always be confirmed as suitable for steam sterilization before processing.

What is included with a refurbished autoclave?

Included accessories and configurations can vary between individual units. Customers should review the product listing and speak with American Instrument Exchange to confirm included baskets, trays, accessories, documentation, and other components before purchase.

Does this refurbished autoclave include a warranty?

Unless otherwise specified, refurbished autoclaves sold by American Instrument Exchange include a 90-day warranty.

Can American Instrument Exchange help determine whether this autoclave will fit my laboratory?

Yes. Our team can help review chamber capacity, equipment dimensions, electrical requirements, utilities, and expected load types to determine whether the Hirayama HV-50II is appropriate for your facility.

Does American Instrument Exchange also sell new autoclaves?

Yes. In addition to professionally refurbished laboratory autoclaves, American Instrument Exchange offers new Tuttnauer autoclaves for laboratories that prefer new equipment, current manufacturer support, or a factory warranty.

Testing Procedures for Used and Refurbished Laboratory Equipment

Ensure Accuracy, Safety, and Dependable Performance Across Applications

At American Instrument Exchange, all used and refurbished laboratory equipment undergoes a rigorous, multi-point testing protocol to ensure optimal performance, operational safety, and long-term reliability. Whether the equipment is destined for research, diagnostics, quality control, or production environments, our thorough inspection and testing process is designed to meet the highest standards of laboratory excellence.

Why Testing Used Lab Equipment Is Essential

Before any refurbished laboratory equipment is returned to service, it must be carefully tested to verify:

• Functional integrity and operational performance
• Setpoint accuracy and repeatability (where applicable)
• User interface responsiveness and control features

Proper testing reduces the risk of equipment failure, measurement inaccuracies, or user hazards—helping to ensure consistent results in clinical, academic, biotech, and industrial labs.

Our standardized lab equipment testing procedures are tailored to each equipment type, ensuring every unit meets manufacturer specifications and industry benchmarks.

Key Testing Procedures for Refurbished and Used Laboratory Equipment

1. Initial Visual Inspection

• Examine equipment housing for signs of wear, corrosion, or damage
• Check ports, power cords, and exterior components for tampering or deterioration
• Verify that internal and external parts (racks, shelves, connectors, accessories) are present and undamaged

2. Functional Startup and Operational Testing

• Power on the equipment and verify startup diagnostics
• Confirm functionality of displays, buttons, switches, and control panels
• Run basic functions to confirm proper response and behavior under standard operating conditions

3. Testing and Performance Verification

• Test internal sensors or control systems using industry-standard tools
• Perform operational tests to validate accuracy and consistency
• Verify key performance specifications such as temperature control, timing, speed, or measurement outputs, depending on equipment type

4. Mechanical and Electrical System Testing

• Evaluate motors, pumps, fans, or other moving parts for smooth operation
• Inspect and test wiring, relays, fuses, and circuit boards for safety and reliability
• Test power delivery and grounding compliance

5. Safety and Compliance Checks

• Ensure equipment is grounded and insulated to meet laboratory safety standards
• Test alarms, interlocks, emergency stops, or safety shutdown systems if applicable

6. Final Quality Assurance and Documentation

• Perform extended runtime testing
• Document operational logs, testing results, and any repairs or adjustments made
• Complete a final inspection, thorough cleaning, and packaging for delivery

Trusted Quality from American Instrument Exchange

With over 50 years of experience in laboratory equipment refurbishment, American Instrument Exchange is committed to delivering certified, lab-ready instruments backed by expert testing. Our testing protocols ensure that each piece of equipment—regardless of type—is safe, accurate, and dependable from day one.

Whether you're equipping a startup lab or expanding a high-throughput facility, you can count on our refurbished laboratory equipment to perform with precision and reliability.

Refurbishment Protocol for Used Laboratory Equipment from American Instrument Exchange

At American Instrument Exchange, every piece of used laboratory equipment we offer undergoes a multi-step refurbishment process. Whether it's an analytical balance, centrifuge, freezer, oven, or any other essential lab instrument, our goal is to restore each unit to peak performance—ensuring accuracy, safety, and long-term reliability in scientific, clinical, industrial, and academic environments.

Why Choose Refurbished Lab Equipment from American Instrument Exchange?

• Thoroughly tested for performance, precision, and safety
• Backed by a warranty
• A cost-effective alternative to new equipment
• Environmentally sustainable through equipment reuse and waste reduction
• Serviced by expert technicians with decades of laboratory equipment experience

Step-by-Step Refurbishment Protocol

Every instrument and system refurbished at American Instrument Exchange follows a detailed, industry-aligned process:

1. Initial Intake & Inspection

• Complete visual and structural inspection for cosmetic damage, wear, or corrosion
• Mechanical assessment of hinges, seals, fasteners, motors, and moving parts
• Missing components and damaged items are documented for repair or replacement

2. Cleaning and Decontamination

• Full internal and external cleaning using non-abrasive, lab-safe solutions
• Removal of biological, chemical, or particulate contamination
• Disassembly and cleaning of removable parts such as trays, shelves, and filters

3. Mechanical and Electrical Repair

• Replacement or repair of worn or broken mechanical parts
• Evaluation and servicing of control panels, sensors, switches, and displays
• Testing and repair of electrical wiring, fuses, circuit boards, and power supplies

4. Functional System Testing

• Assessment of all major functions specific to the equipment type (e.g., speed, temperature, force, weight, timing)
• Operation of control interfaces, programming menus, and digital displays
• Verification of stabilization time, responsiveness, and user input reliability

5. Testing and Performance Verification

• Testing of internal sensors, controllers, and measurement systems using certified tools
• Multi-point testing to ensure repeatability, accuracy, and performance consistency
• Confirmation of user-defined setpoints, timing sequences, or programmable cycles

6. Safety and Compliance Checks

• Testing of safety interlocks, alarms, and over-limit protection systems (as applicable)
• Electrical safety inspections, including grounding and insulation verification

7. Final Quality Assurance and Documentation

• Full operational testing under simulated lab conditions
• Completion of performance benchmarks, testing  results, and repair logs
• Final cleaning and visual inspection

Trust the Experts at American Instrument Exchange

With over 50 years of experience in the laboratory equipment industry, American Instrument Exchange is a trusted leader in high-quality refurbished lab instruments. Our refurbishment protocols ensure that every piece of equipment we sell is lab-ready—offering the precision, performance, and durability your team can count on.

Whether you’re outfitting a new lab or expanding an existing operation, choose American Instrument Exchange for tested, warrantied, and cost-effective laboratory equipment.

Warranty Information

All used equipment sold by American Instrument Exchange is refurbished/reconditioned, tested to meet specifications, cleaned, and comes with a 90-day warranty from the date of shipment unless otherwise specified. New products include a warranty from the manufacturer. Your warranty is only valid if you have paid your invoice. If your invoice is over 30 days old, warranty work will not be performed until your invoice is paid in full.  American Instrument Exchange is not liable for any special or consequential damages that result from the use of, or the inability to use, the materials on this site or the performance of the products,

Exceptions include international sales and items that are agreed to be sold with a lesser warranty or items that are agreed to be sold “as is.”

Should there be visible shipping damage to packaging or concealed shipping damage to item(s) supplied, buyer must communicate such damage to the delivering entity or carrier upon receipt first and to American Instrument the same day item is accepted / signed for. Failure to do so voids warranty. Customer decision to involve / procure third party or OEM service other than American Instrument or AIE assigned vendors to resolve in-warranty instrument failure or defect without first placing a service call to American Instrument voids warranty.

Return & Cancellation Policy

American Instrument Exchange will authorize the return of and issue a full refund for any equipment that is not working as represented and could not be replaced or repaired to the customer’s satisfaction by AIE or a representative of AIE during the warranty period. Returns without prior authorization and an RMA number will not be accepted. 

Customers are responsible for proper packaging of the equipment and all included accessories. American Instrument will pay for insurance and shipping costs. Non-inventory items bought specifically to fill customer orders may possibly be returned, but on a case by case basis.

Customers who cancel orders after refurbishing has begun or after delivery where there are no equipment performance issues may be subject to a Restocking/Cancellation Fee of 20% or more and responsible for shipping costs for both the delivery and return.

Ongoing and Extended Support Options

American Instrument Exchange is able to provide additional repair and support services outside the warranty terms for most products that sell.

For biosafety cabinets, clean benches, chemical fume hoods, and other clean air products our team at AIE Laboratory Services can provide certifications, repairs, decontaminations, and other services for customers throughout New England, and guidance and limited technical assistance for any customers in the US and Canada for new or refurbished biosafety cabinets purchased from American Instrument Exchange.

For all other products, the repair service team at American Instrument Exchange can provide both field and depot repair evaluations. We can easily schedule and coordinate the pick-up and transportation of your malfunctioning equipment. By offering hourly rates lower than most OEM service providers and eliminating travel time for technicians, we help reduce repair costs. Furthermore, our lab depot repair service minimizes or eliminates scheduling delays. Our experienced service technicians are qualified to restore your equipment to factory specifications.

Please contact our team at info@americaninstrument.com for more details.

FAQ

Does the equipment come with a warranty?

Yes, all equipment from American Instrument Exchange comes with a warranty.
Used/reconditioned/refurbished equipment is tested to make sure it operates to the manufacturer's specifications and comes with a 90-day warranty (unless otherwise noted). New equipment comes with a warranty from the manufacturer.

How do you test and recondition the equipment?

Testing requirements vary across all the equipment categories we sell. Temperature controlled units are tested with NIST traceable probes and data loggers. Gaskets, external housing, glass, handles, controls and control screens are all thoroughly inspected for integrity and functionality.
We test all equipment using the manufacturer's parameters and specifications to confirm that the unit operates properly.

How do products ship from American Instrument Exchange?

We can ship products both nationally and internationally using a well-established network of transporters. Smaller items will ship via UPS. Larger equipment will be palletized and shipped either LTL or air-ride, depending on the specific equipment and/or delivery requirements.

Return and order cancellation policy

American Instrument Exchange will accept the return of any product that is not working as represented and could not be replaced or repaired to the customer's satisfaction during the warranty period. Customers who cancel orders after refurbishing has begun will be subject to a cancellation and restocking fee of between 20% and 40%.

Are discounts available for educational or non-profit institutions, or for bulk purchases?

Yes – call or email us today with a list of equipment you're looking for and we can potentially put together a quote that includes a discount.

How does your price matching policy work?

We strive to keep our pricing competitive and reasonable. If you find comparable items for sale at a lower price from other vendors please send us a link and or quote for the item and we'll do our best to match or beat the price.

Can I see the equipment in person before committing to a purchase?

Customers are welcome to make an appointment to view equipment in our warehouse. Given our workload we may not be able to test or clean the equipment prior to your arrival if you have not committed to an order.

1023 Western Avenue is a working warehouse, not a showroom, and customers should dress appropriately and wear closed toe shoes.

Can I ship products that I purchased elsewhere to American Instrument for repair?

Yes – please see our repair services page for more information.